ICD-10 Code G37.0 – Diffuse sclerosis of central nervous system (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diffuse sclerosis of central nervous system is G37.0.
2026 ICD-10-CM Diagnosis Code G37.0 – Diffuse sclerosis of central nervous system

What it is

G37.0 identifies diffuse sclerosis of the central nervous system, a rare demyelinating disorder affecting brain and spinal cord tissue. Use it when the record specifically documents this diagnosis.

Clinical signs

Clinical features vary; refer to documentation. Standard references describe progressive neurologic dysfunction with signs of white matter involvement, such as weakness, coordination problems, or cognitive changes.

When to use this code

Use G37.0 when the provider clearly states diffuse sclerosis of the central nervous system in the assessment, problem list, or discharge diagnosis. It may also apply when the condition is confirmed after evaluation of progressive demyelinating disease. If the note uses only a broad neurologic symptom description, check documentation before coding.

Do not use for

Do not use this code for nonspecific dizziness, weakness, or gait disturbance without a documented diagnosis. Do not substitute it for other demyelinating disorders unless the record specifically supports diffuse sclerosis.

Coding tip

Code the documented diagnosis, not the suspected neurologic syndrome; if the wording is unclear, query the provider.

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