ICD-10 Code F55 – Abuse of non-psychoactive substances (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Abuse of non-psychoactive substances is F55.
2026 ICD-10-CM Diagnosis Code F55 – Abuse of non-psychoactive substances

What it is

F55 identifies harmful or excessive use of substances that are not typically psychoactive, such as laxatives, vitamins, or other non-drug products. Use it when the behavior itself is the diagnosis, not an intoxication or dependence disorder.

Clinical signs

Clinical features vary; refer to documentation. You may see repeated overuse, persistent preoccupation with the substance, or adverse effects related to chronic misuse.

When to use this code

Use F55 when the record clearly states abuse of a non-psychoactive substance and the substance is being used in a harmful pattern. It may apply when the chart documents excessive self-administration, misuse, or related complications. Check documentation for the exact substance and intent.

Do not use for

Do not use this code for poisoning, adverse drug reactions, or dependence on psychoactive substances. If the substance is unspecified or the diagnosis is unclear, check documentation.

Coding tip

Capture the specific non-psychoactive substance in the note whenever possible, because F55 alone does not identify the product involved.

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