ICD-10 Code F13.221 – Sedative, hypnotic or anxiolytic dependence with intoxication delirium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F13.221 – Sedative, hypnotic or anxiolytic dependence with intoxication delirium
What it is
This code identifies sedative, hypnotic, or anxiolytic dependence with delirium caused by intoxication. Use it when the record shows both dependence and an acute delirious state linked to the substance.
Clinical signs
Typical findings include confusion, disorientation, impaired attention, and fluctuating awareness consistent with delirium. Clinical features vary; refer to documentation for evidence of intoxication and dependence.
When to use this code
Use this code when documentation states the patient has dependence on a sedative, hypnotic, or anxiolytic and the current episode includes intoxication delirium. You should also use it when the clinician explicitly links delirium to the substance. Check documentation if the note does not clearly identify both conditions.
Do not use for
Do not use this code for uncomplicated dependence without delirium, or for delirium from another cause. If the substance is not a sedative, hypnotic, or anxiolytic, select the appropriate code instead.
Coding tip
Confirm that the provider documents both dependence and intoxication delirium before assigning F13.221.