ICD-10 Code F11.24 – Opioid dependence with opioid-induced mood disorder (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F11.24 – Opioid dependence with opioid-induced mood disorder
What it is
F11.24 identifies opioid dependence with a mood disorder caused by opioid use. Use it when the record shows both opioid dependence and a clinician-documented opioid-induced depressive, bipolar, or other mood disturbance.
Clinical signs
Clinical features vary; refer to documentation. You may see persistent low mood, emotional lability, or other mood symptoms attributed to opioid use, along with evidence of dependence such as compulsive use or difficulty stopping.
When to use this code
Use this code when the provider clearly links the mood disorder to opioid use and documents opioid dependence. It fits encounters where the mood condition is not better explained by an independent psychiatric diagnosis.
If the chart only notes opioid use with depression, check documentation for whether the mood disorder is substance-induced. Code the dependence and the opioid-induced mood disorder only when both are supported.
Do not use for
Do not use F11.24 for uncomplicated opioid dependence without a mood disorder. Also avoid it when the mood disorder is unrelated to opioids or when documentation does not clearly establish the causal link.
Coding tip
Look for explicit provider wording such as “opioid-induced mood disorder” or equivalent, and query if the relationship between opioid use and mood symptoms is unclear.