ICD-10 Code F11.2 – Opioid Dependence (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code F11.2 – Opioid dependence
What it is
F11.2 identifies opioid dependence, meaning a pattern of opioid use with impaired control, continued use despite harm, and physiologic adaptation. Use it when documentation clearly states dependence rather than simple use or abuse.
Clinical signs
Common findings include craving, tolerance, withdrawal, and difficulty reducing use. Clinical features vary; refer to documentation.
When to use this code
Use F11.2 when the provider documents opioid dependence, opioid use disorder with dependence, or a similar confirmed diagnosis. It may apply in outpatient, inpatient, or emergency records when the condition is actively assessed. If the note is unclear, check documentation before coding.
Do not use for
Do not use this code for uncomplicated opioid use, acute intoxication, or opioid poisoning. If the record only shows prescribed opioid therapy without dependence, choose a more specific code or check documentation.
Coding tip
Code dependence only when the provider explicitly supports it; do not infer it from medication history alone.