ICD-10 Code E77 – Disorders of glycoprotein metabolism (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Disorders of glycoprotein metabolism is E77.
2026 ICD-10-CM Diagnosis Code E77 – Disorders of glycoprotein metabolism

What it is

E77 identifies inherited disorders that affect glycoprotein metabolism, a process involved in making and breaking down glycoproteins in the body. Use it for documented metabolic conditions in this category, not for nonspecific protein problems.

Clinical signs

Clinical features vary; refer to documentation. Presentations may include developmental delay, organ involvement, neurologic findings, or other signs of an inherited metabolic disorder, depending on the specific glycoprotein defect.

When to use this code

Use E77 when the provider documents a disorder of glycoprotein metabolism or a related inherited glycosylation defect. It is appropriate when the diagnosis is established, suspected as a metabolic condition, or supported by specialist evaluation. Check documentation for the exact disorder if a more specific code is available.

Do not use for

Do not use E77 for acquired malnutrition, general liver disease, or unspecified metabolic abnormalities. If the record names a different inborn error of metabolism, code that condition instead.

Coding tip

Look for the exact metabolic diagnosis name in the chart and code the most specific documented condition first.

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