ICD-10 Code E72.549 – Secondary hyperoxaluria, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Secondary hyperoxaluria, unspecified is E72.549.
2026 ICD-10-CM Diagnosis Code E72.549 – Secondary hyperoxaluria, unspecified

What it is

Use this code for secondary hyperoxaluria when the cause is not further specified. It describes excessive oxalate in the body due to an acquired condition, not a primary inherited disorder.

Clinical signs

Clinical features vary; refer to documentation. Patients may have kidney stones, hematuria, or recurrent urinary symptoms, but the record should support secondary hyperoxaluria rather than another oxalate disorder.

When to use this code

Assign this code when the clinician documents secondary hyperoxaluria and does not identify a more specific cause. Use it for confirmed acquired hyperoxaluria, including cases linked to malabsorption or other secondary conditions if not otherwise coded.

If the note only mentions elevated urine oxalate without a diagnosis, check documentation before coding. Report the more specific code when the underlying cause or a different oxalate disorder is stated.

Do not use for

Do not use this code for primary hyperoxaluria or for kidney stones alone. Also avoid it when the chart documents a specific secondary cause that should be coded instead.

Coding tip

Look for explicit wording of “secondary hyperoxaluria” in the assessment, and code the underlying condition separately when documented.

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