ICD-10 Code E72.54 – Secondary hyperoxaluria (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E72.54 – Secondary hyperoxaluria
What it is
Secondary hyperoxaluria means excess oxalate in the body caused by an external or acquired factor, not a primary inherited disorder. It is often linked to intestinal disease, malabsorption, or other documented causes.
Clinical signs
Clinical features vary; refer to documentation. Commonly documented findings include recurrent calcium oxalate kidney stones, nephrocalcinosis, or elevated urinary oxalate in the setting of an acquired cause.
When to use this code
Use E72.54 when the record specifically identifies secondary hyperoxaluria or clearly documents acquired oxalate excess. Code it for patients with malabsorption-related oxalate overproduction or other noninherited causes when supported by the provider’s note.
Do not assume this diagnosis from kidney stones alone. If the chart only mentions hyperoxaluria without a secondary cause, check documentation before assigning this code.
Do not use for
Do not use this code for primary hyperoxaluria or unspecified hyperoxaluria. Also avoid it when oxalate excess is not documented or the cause is unclear.
Coding tip
Confirm that the provider links hyperoxaluria to a secondary cause before coding E72.54.