ICD-10 Code E71.518 – Other disorders of peroxisome biogenesis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E71.518 – Other disorders of peroxisome biogenesis
What it is
E71.518 identifies a peroxisome biogenesis disorder not otherwise specified elsewhere. Use it when documentation shows abnormal peroxisome formation or function, but the record does not support a more specific peroxisomal diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Common references describe developmental delay, hypotonia, seizures, vision or hearing problems, and liver or neurologic involvement in peroxisomal disorders.
When to use this code
Use this code when the clinician documents a peroxisome biogenesis disorder and does not name a more specific subtype. It may also fit cases described as “other” or unspecified peroxisomal biogenesis abnormalities. Check documentation if genetic or biochemical details are incomplete.
Do not use for
Do not use it for a clearly identified peroxisomal syndrome or another metabolic disorder with its own code. Do not assume this code from nonspecific neurologic or hepatic findings alone.
Coding tip
Code from the provider’s exact wording, and confirm whether a more specific peroxisomal diagnosis is documented before assigning E71.518.