ICD-10 Code E28.310 – Symptomatic Premature Menopause (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Symptomatic premature menopause is E28.310.
2026 ICD-10-CM Diagnosis Code E28.310 – Symptomatic premature menopause

What it is

E28.310 identifies premature menopause when symptoms are documented. Use it for menopause occurring earlier than expected, with bothersome menopausal features noted in the record.

Clinical signs

Common findings include amenorrhea or irregular menses with menopausal symptoms such as hot flashes, night sweats, or vaginal dryness. Clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents premature menopause and also notes symptoms. It fits outpatient or inpatient records where the diagnosis is stated clearly and the symptom burden is part of the assessment.

If the chart only says menopause without symptom detail, check documentation before assigning this code. You should code the documented condition, not infer symptoms from age alone.

Do not use for

Do not use it for uncomplicated premature menopause without symptoms. Do not use it for perimenopause, amenorrhea from another cause, or unclear documentation; check documentation.

Coding tip

Assign E28.310 only when both premature menopause and symptoms are clearly documented.

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