ICD-10 Code E28.3 – Primary ovarian failure (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E28.3 – Primary ovarian failure
What it is
E28.3 identifies primary ovarian failure, a condition where the ovaries do not function normally and fail to produce adequate hormones or eggs. It is used when the diagnosis is documented and supported by the record.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include absent or irregular menses, infertility, and signs of estrogen deficiency. Confirm the diagnosis from the provider’s assessment rather than symptoms alone.
When to use this code
Use E28.3 when the provider documents primary ovarian failure, premature ovarian insufficiency, or ovarian failure as the established condition. Code it for encounters focused on evaluation, monitoring, or counseling related to the disorder. If the record is unclear, check documentation before assigning the code.
Do not use for
Do not use this code for normal menopause, unspecified amenorrhea, or infertility without documented ovarian failure. If the chart only suggests endocrine dysfunction, check documentation for the confirmed diagnosis.
Coding tip
Assign E28.3 only when the provider clearly links the ovarian failure diagnosis to the encounter.