ICD-10 Code E28.0 – Estrogen Excess (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code E28.0 – Estrogen excess
What it is
E28.0 identifies estrogen excess, a condition where estrogen levels are higher than expected for the clinical context. Use it when documentation states excess estrogen or a similar diagnosis.
Clinical signs
Clinical features vary; refer to documentation. Common references may note menstrual changes, breast tenderness, or other findings linked to estrogen dominance, but the record should support the diagnosis.
When to use this code
Use E28.0 when the provider clearly documents estrogen excess as the assessed condition. It may apply in endocrine evaluations, hormone-related workups, or follow-up visits where the diagnosis is confirmed. If the note only mentions abnormal hormone testing without a diagnosis, check documentation.
Do not use for
Do not use this code for nonspecific hormonal complaints or for estrogen therapy use without documented excess. If the record reflects another endocrine disorder or an uncertain finding, code the documented condition instead.
Coding tip
Confirm that the provider names estrogen excess explicitly; otherwise, query or code the documented abnormality only.