ICD-10 Code E10.351 – Type 1 diabetes mellitus with proliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Type 1 diabetes mellitus with proliferative diabetic retinopathy with macular edema is E10.351.
2026 ICD-10-CM Diagnosis Code E10.351 – Type 1 diabetes mellitus with proliferative diabetic retinopathy with macular edema

What it is

This code identifies type 1 diabetes with proliferative diabetic retinopathy and macular edema. It means the diabetic eye disease has progressed to abnormal retinal vessel growth and swelling in the macula.

Clinical signs

Findings may include neovascularization, retinal hemorrhage, and macular thickening or edema on eye examination. Vision may be blurred or reduced, but clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents type 1 diabetes with proliferative diabetic retinopathy and macular edema in the same eye or both eyes. It also applies when ophthalmology or endocrinology notes clearly support both the proliferative stage and macular edema. If the record does not specify these elements, check documentation before coding.

Do not use for

Do not use this code for nonproliferative diabetic retinopathy, diabetic macular edema without proliferative disease, or retinopathy due to another cause. Do not assume laterality or severity that is not documented.

Coding tip

Confirm that both proliferative retinopathy and macular edema are documented before assigning E10.351.

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