ICD-10 Code E09.351 – Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema is E09.351.
2026 ICD-10-CM Diagnosis Code E09.351 – Drug or chemical induced diabetes mellitus with proliferative diabetic retinopathy with macular edema

What it is

This code identifies diabetes caused by a drug or chemical, with proliferative diabetic retinopathy and macular edema in one or both eyes. It reflects a documented medication- or substance-induced diabetic eye complication.

Clinical signs

Findings may include retinal neovascularization, vitreous hemorrhage, or other proliferative changes, along with macular swelling. Clinical features vary; refer to documentation.

When to use this code

Use this code when the record clearly links diabetes to a drug or chemical and also documents proliferative diabetic retinopathy with macular edema. The eye condition must be part of the diagnosis, not just a history of diabetes or retinopathy. Check documentation if the cause or eye laterality is unclear.

Do not use for

Do not use this code for diabetes without a drug or chemical cause, or for nonproliferative retinopathy without macular edema. Do not assign it if the chart does not support both the diabetes type and the eye complication.

Coding tip

Verify the causal agent and the ophthalmic diagnosis in the same record before coding E09.351.

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