ICD-10 Code A50.43 – Late congenital syphilitic polyneuropathy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code A50.43 – Late congenital syphilitic polyneuropathy
What it is
This code identifies peripheral nerve damage that appears later in life as a complication of congenital syphilis. It reflects neurologic involvement linked to infection acquired before birth.
Clinical signs
Clinical features vary; refer to documentation. Findings may include sensory loss, weakness, pain, or other peripheral neuropathy signs in a patient with confirmed or suspected congenital syphilis.
When to use this code
Use A50.43 when the record specifically documents late congenital syphilitic polyneuropathy. Code it when the clinician links the neuropathy to congenital syphilis rather than to another cause.
Use supporting documentation that shows a congenital syphilis history and a later neurologic manifestation. If the cause is unclear, check documentation before assigning this code.
Do not use for
Do not use this code for acquired syphilis, unspecified neuropathy, or neuropathy from diabetes, alcohol, or other causes. Check documentation if congenital origin is not stated.
Coding tip
Assign A50.43 only when the provider explicitly connects the neuropathy to late congenital syphilis.