ICD-10 Code D83.0 – Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D83.0 – Common variable immunodeficiency with predominant abnormalities of B-cell numbers and function
What it is
D83.0 identifies a form of common variable immunodeficiency where the main problem is abnormal B-cell number or function. It reflects an immune system disorder that can leave the patient more vulnerable to infections.
Clinical signs
Typical findings include recurrent or persistent bacterial infections, especially of the sinuses, ears, or lungs. Clinical features vary; refer to documentation for B-cell abnormalities and the specific immune deficiency pattern.
When to use this code
Use D83.0 when the record clearly documents common variable immunodeficiency with predominant B-cell number or function abnormalities. Apply it for confirmed diagnoses, not for suspected immune deficiency or nonspecific recurrent infections alone.
If the note describes CVID but does not specify the B-cell predominance, check documentation before coding. Code only when the clinician links the condition to this subtype or equivalent wording.
Do not use for
Do not use this code for other specified immunodeficiencies, isolated antibody deficiency, or transient low immunoglobulin findings without a documented CVID diagnosis. Check documentation when the subtype is unclear.
Coding tip
Look for wording that ties CVID to B-cell number or function abnormalities, and query the provider if the subtype is not explicitly stated.