ICD-10 Code D72.11 – Hypereosinophilic syndrome [HES] (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code D72.11 – Hypereosinophilic syndrome [HES]
What it is
D72.11 identifies hypereosinophilic syndrome, a disorder marked by persistent eosinophilia with organ involvement. Use it when documentation shows HES rather than a temporary or secondary eosinophil elevation.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include unexplained eosinophilia and evidence of damage to organs such as the skin, lungs, heart, or nervous system.
When to use this code
Use D72.11 when the provider diagnoses hypereosinophilic syndrome or documents HES. It also fits follow-up visits for a confirmed condition, even if the encounter is for monitoring rather than active treatment.
Code it only when the record supports a true syndrome, not just an isolated abnormal eosinophil count. If the chart does not clearly establish HES, check documentation before assigning this code.
Do not use for
Do not use D72.11 for eosinophilia caused by allergies, parasites, drugs, or other secondary conditions. It is also wrong for a lab abnormality alone without a documented syndrome.
Coding tip
Look for provider wording that links eosinophilia with systemic or organ involvement before you assign D72.11.