ICD-10 Code D49.6 – Neoplasm of unspecified behavior of brain (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Neoplasm of unspecified behavior of brain is D49.6.
2026 ICD-10-CM Diagnosis Code D49.6 – Neoplasm of unspecified behavior of brain

What it is

D49.6 identifies a brain neoplasm whose behavior is not specified as benign or malignant. Use it when the record documents a brain tumor or mass, but the pathology or clinical note does not define its behavior.

Clinical signs

Clinical features vary; refer to documentation. Patients may have neurologic findings consistent with an intracranial mass, but the code itself reflects the unspecified behavior, not a specific symptom pattern.

When to use this code

Use this code when the provider documents a neoplasm of the brain and does not state whether it is benign, malignant, or of uncertain behavior. It is also appropriate when the chart confirms a brain tumor, but supporting details are incomplete. Check documentation before assigning a more specific neoplasm code.

Do not use for

Do not use D49.6 when the record clearly identifies a benign, malignant, or uncertain brain neoplasm. Do not use it for nonspecific headache, seizure, or other symptoms without documentation of a brain neoplasm.

Coding tip

If the behavior is not documented, query the provider rather than assuming a more specific neoplasm code.

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