ICD-10 Code D47.2 – Monoclonal gammopathy (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Monoclonal gammopathy is D47.2.
2026 ICD-10-CM Diagnosis Code D47.2 – Monoclonal gammopathy

What it is

D47.2 identifies monoclonal gammopathy, a condition where one clone of plasma cells makes a single abnormal protein. It is often found on testing and may be incidental.

Clinical signs

Clinical features vary; refer to documentation. Many patients have no symptoms, while others may show an abnormal serum protein pattern or evidence of a plasma cell disorder.

When to use this code

Use D47.2 when the record documents monoclonal gammopathy or MGUS without a more specific diagnosis. It fits evaluations for an unexplained monoclonal protein when the provider has not confirmed malignancy or another plasma cell disorder. Check documentation if the note suggests multiple myeloma, amyloidosis, or another defined condition.

Do not use for

Do not use this code for confirmed multiple myeloma, Waldenström macroglobulinemia, or other specified neoplasms. If the chart names a different plasma cell disorder, code that diagnosis instead.

Coding tip

Assign D47.2 only when the provider documents monoclonal gammopathy and no more specific diagnosis is established.

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