ICD-10 Code D21.4 – Benign neoplasm of connective and other soft tissue of abdomen (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Benign neoplasm of connective and other soft tissue of abdomen is D21.4.
2026 ICD-10-CM Diagnosis Code D21.4 – Benign neoplasm of connective and other soft tissue of abdomen

What it is

This code identifies a noncancerous growth arising from connective or other soft tissues in the abdominal area. It indicates a benign mass, not a malignant tumor.

Clinical signs

Clinical features vary; refer to documentation. Patients may have a palpable abdominal mass, localized discomfort, or incidental imaging findings, but the diagnosis should be supported by provider documentation.

When to use this code

Use D21.4 when the provider documents a benign neoplasm of connective or other soft tissue located in the abdomen. This applies to confirmed benign soft tissue tumors, whether found during workup for pain, swelling, or an incidental mass. If the record does not clearly identify the tissue type or location, check documentation.

Do not use for

Do not use this code for malignant abdominal tumors, unspecified abdominal masses, or lesions documented as cysts or inflammatory processes. If the diagnosis is not clearly benign, check documentation.

Coding tip

Verify both benign behavior and abdominal site in the provider note before assigning D21.4.

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