ICD-10 Code D21.10 – Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder is D21.10.
2026 ICD-10-CM Diagnosis Code D21.10 – Benign neoplasm of connective and other soft tissue of unspecified upper limb, including shoulder

What it is

This code identifies a noncancerous growth arising from connective or other soft tissue in an upper limb, including the shoulder, when the exact site is not specified. Use it when documentation confirms a benign soft-tissue neoplasm but does not name a more precise location.

Clinical signs

Findings often include a localized soft-tissue mass, swelling, or a palpable lump. Clinical features vary; refer to documentation and pathology, imaging, or operative notes that support a benign soft-tissue tumor.

When to use this code

Use this code when the record states a benign neoplasm of connective or other soft tissue in the upper limb or shoulder, but the exact anatomic site is not documented. It also fits when the lesion is confirmed benign and no more specific ICD-10-CM option is supported. If laterality or a more precise site is available, code to that level instead.

Do not use for

Do not use this code for malignant, uncertain, or unspecified neoplasms without benign confirmation. Do not assign it when the documentation identifies a specific upper-limb soft-tissue site that has a more exact code.

Coding tip

Check the pathology or provider note for the exact site and behavior before defaulting to the unspecified code.

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