ICD-10 Code C92.40 – Acute promyelocytic leukemia, not having achieved remission (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Acute promyelocytic leukemia, not having achieved remission is C92.40.
2026 ICD-10-CM Diagnosis Code C92.40 – Acute promyelocytic leukemia, not having achieved remission

What it is

This code identifies acute promyelocytic leukemia that is still active and has not gone into remission. Use it when the record clearly states APL without remission or equivalent wording.

Clinical signs

Clinical features vary; refer to documentation. Commonly, the record may describe acute leukemia findings, abnormal promyelocytes, and related marrow or blood evidence supporting APL.

When to use this code

Use C92.40 when the provider documents acute promyelocytic leukemia and specifically states it has not achieved remission. It also fits when the note indicates persistent active disease after prior therapy. If remission status is unclear, check documentation before coding.

Do not use for

Do not use this code for APL in remission or for cases where the documentation only says leukemia without specifying promyelocytic type. Check documentation if the remission status is missing.

Coding tip

Code the remission status exactly as documented, because APL has separate ICD-10-CM codes for remission and non-remission.

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