ICD-10 Code C92.4 – Acute promyelocytic leukemia (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C92.4 – Acute promyelocytic leukemia
What it is
C92.4 identifies acute promyelocytic leukemia, a specific subtype of acute myeloid leukemia. It is used when documentation names promyelocytic leukemia or APL.
Clinical signs
Clinical features vary; refer to documentation. Common findings include acute leukemia symptoms such as fatigue, infection, bruising, or bleeding, with promyelocytes noted in the record.
When to use this code
Use C92.4 when the provider documents acute promyelocytic leukemia, including APL or promyelocytic leukemia. Code it from confirmed diagnoses in the assessment, pathology, or discharge summary. If the record only says acute leukemia without subtype, check documentation.
Do not use for
Do not use this code for other acute myeloid leukemia subtypes or for chronic leukemias. If the diagnosis is unspecified leukemia or unclear, check documentation before assigning C92.4.
Coding tip
Confirm the leukemia subtype in the final provider diagnosis, not just in lab or pathology language.