ICD-10 Code C91.A2 – Mature B-cell leukemia Burkitt-type, in relapse (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C91.A2 – Mature B-cell leukemia Burkitt-type, in relapse
What it is
C91.A2 identifies relapse of mature B-cell leukemia, Burkitt-type. Use it when this specific leukemia has returned after prior remission or treatment, and documentation clearly states relapse.
Clinical signs
Findings may include recurrent leukemia symptoms such as fatigue, cytopenia-related issues, lymphadenopathy, or organ involvement. Clinical features vary; refer to documentation.
When to use this code
Use this code when the record documents Burkitt-type mature B-cell leukemia as relapsed, recurrent, or returning after remission. It applies when the provider specifies relapse rather than initial diagnosis or persistent disease. If the note only says “history of leukemia” or lacks recurrence details, check documentation.
Do not use for
Do not use it for active disease without relapse, remission status, or unspecified mature B-cell neoplasms. Do not assign it when the chart does not clearly identify Burkitt-type leukemia in relapse.
Coding tip
Confirm the provider documents relapse, not persistence or progression, before selecting C91.A2.