ICD-10 Code C90.10 – Plasma cell leukemia not having achieved remission (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C90.10 – Plasma cell leukemia not having achieved remission
What it is
C90.10 identifies plasma cell leukemia that has not achieved remission. Use it for a documented plasma cell neoplasm with circulating malignant plasma cells when the condition remains active.
Clinical signs
Clinical features vary; refer to documentation. Common findings in plasma cell leukemia may include marked plasma cell burden in blood, systemic symptoms, anemia, bone pain, renal impairment, or other signs of aggressive disease.
When to use this code
Use C90.10 when the provider documents plasma cell leukemia and states that remission has not been achieved. This includes initial diagnosis, persistent active disease, or ongoing disease after prior therapy when remission is not documented.
Code the condition as written in the record; do not assume remission status from treatment history alone. If the note is unclear about response to therapy, check documentation.
Do not use for
Do not use this code for plasma cell leukemia in remission or for other plasma cell disorders without leukemia. If the record only says multiple myeloma or plasmacytoma, choose the documented diagnosis instead.
Coding tip
Verify both the leukemia diagnosis and the explicit “not in remission” wording before assigning C90.10.