ICD-10 Code C83.39 – Diffuse large B-cell lymphoma, extranodal and solid organ sites (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diffuse large B-cell lymphoma, extranodal and solid organ sites is C83.39.
2026 ICD-10-CM Diagnosis Code C83.39 – Diffuse large B-cell lymphoma, extranodal and solid organ sites

What it is

C83.39 identifies diffuse large B-cell lymphoma arising outside lymph nodes, in extranodal tissue or a solid organ. Use it when the record specifies this lymphoma subtype and location.

Clinical signs

Clinical features vary; refer to documentation. Commonly, records describe a rapidly enlarging mass or organ-specific symptoms with biopsy confirming diffuse large B-cell lymphoma.

When to use this code

Use C83.39 when the provider documents diffuse large B-cell lymphoma in an extranodal site such as gastrointestinal tissue, skin, or another solid organ. You should code it when the site is clearly stated and the diagnosis is confirmed or treated as active lymphoma.

Do not use for

Do not use this code for nodal lymphoma without extranodal involvement, or for other B-cell lymphoma subtypes. Check documentation if the site is unspecified or if the record only says “lymphoma.”

Coding tip

Verify both the lymphoma subtype and the extranodal site before assigning C83.39.

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