ICD-10 Code C83.37 – Diffuse large B-cell lymphoma, spleen (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C83.37 – Diffuse large B-cell lymphoma, spleen
What it is
C83.37 identifies diffuse large B-cell lymphoma involving the spleen. Use it when the documentation specifies this aggressive non-Hodgkin lymphoma as arising in or affecting the spleen.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include splenic enlargement, abdominal fullness, and systemic lymphoma features such as unexplained weight loss, fever, or night sweats.
When to use this code
Use C83.37 when the provider documents diffuse large B-cell lymphoma of the spleen, primary or clearly involving that site. Apply it from pathology, imaging, or oncology notes that specify splenic disease. If the record only says lymphoma without subtype or site, check documentation before coding.
Do not use for
Do not use this code for other B-cell lymphomas, unspecified lymphoma, or splenic enlargement without confirmed lymphoma. If the diagnosis is not clearly documented as diffuse large B-cell lymphoma of the spleen, verify the record.
Coding tip
Code the lymphoma subtype and anatomic site exactly as documented; if either is unclear, query the provider.