ICD-10 Code C81.97 – Hodgkin lymphoma, unspecified, spleen (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Hodgkin lymphoma, unspecified, spleen is C81.97.
2026 ICD-10-CM Diagnosis Code C81.97 – Hodgkin lymphoma, unspecified, spleen

What it is

This code identifies Hodgkin lymphoma involving the spleen when the subtype is not further specified. Use it for documented Hodgkin lymphoma of splenic origin or splenic involvement without a more precise histologic type.

Clinical signs

Clinical features vary; refer to documentation. Patients may have splenic enlargement, abdominal fullness, constitutional “B” symptoms, or imaging and pathology findings consistent with Hodgkin lymphoma.

When to use this code

Use C81.97 when the record clearly states Hodgkin lymphoma, unspecified, spleen, or when the spleen is the documented site and no more specific Hodgkin subtype is given. It may also fit cases where pathology confirms Hodgkin lymphoma in the spleen but the exact subtype is not reported. Check documentation if the site or histology is unclear.

Do not use for

Do not use this code for non-Hodgkin lymphoma, secondary splenic involvement from another primary site, or Hodgkin lymphoma with a specified subtype that has its own code. Check documentation.

Coding tip

Confirm both the lymphoma type and the splenic site in the report before assigning C81.97.

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