ICD-10 Code C81.08 – Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C81.08 – Nodular lymphocyte predominant Hodgkin lymphoma, lymph nodes of multiple sites
What it is
C81.08 identifies nodular lymphocyte predominant Hodgkin lymphoma involving lymph nodes at more than one site. Use it when the diagnosis specifies this Hodgkin lymphoma subtype and multiple nodal regions are affected.
Clinical signs
Patients often present with painless lymph node enlargement, commonly in one or more nodal areas. Clinical features vary; refer to documentation for the confirmed subtype and distribution.
When to use this code
Use this code when the provider documents nodular lymphocyte predominant Hodgkin lymphoma and states that multiple lymph node sites are involved. It may also apply when pathology or oncology notes clearly confirm the subtype with multifocal nodal disease. Check documentation if the site distribution is unclear.
Do not use for
Do not use this code for Hodgkin lymphoma limited to a single nodal region or when the subtype is not specified. Avoid it if the record describes another lymphoma type or only a suspected diagnosis.
Coding tip
Verify both the lymphoma subtype and the “multiple sites” wording in the record before assigning C81.08.