ICD-10 Code C81.07 – Nodular lymphocyte predominant Hodgkin lymphoma, spleen (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Nodular lymphocyte predominant Hodgkin lymphoma, spleen is C81.07.
2026 ICD-10-CM Diagnosis Code C81.07 – Nodular lymphocyte predominant Hodgkin lymphoma, spleen

What it is

C81.07 identifies nodular lymphocyte predominant Hodgkin lymphoma involving the spleen. Use it when documentation specifies this lymphoma subtype and spleen involvement.

Clinical signs

Clinical features vary; refer to documentation. Typical lymphoma findings may include splenic enlargement or other signs of lymphoid malignancy, but the record should clearly support nodular lymphocyte predominant Hodgkin lymphoma in the spleen.

When to use this code

Use this code when the provider documents nodular lymphocyte predominant Hodgkin lymphoma with splenic involvement. It may appear on pathology, oncology, or discharge records when the spleen is named as the involved site. If the site is not specified, check documentation.

Do not use for

Do not use this code for other Hodgkin lymphoma subtypes, non-Hodgkin lymphomas, or generalized lymphoma without spleen documentation. If the record only says “lymphoma” or the site is unclear, check documentation.

Coding tip

Confirm both the subtype and the spleen site in the provider’s wording before assigning C81.07.

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