ICD-10 Code C54.2 – Malignant neoplasm of myometrium (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code C54.2 – Malignant neoplasm of myometrium
What it is
C54.2 identifies a malignant tumor arising in the myometrium, the muscular wall of the uterus. Use it when the record specifically documents cancer of the uterine muscle layer.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include abnormal uterine bleeding, pelvic pain, or an enlarging uterine mass, but you should code only what is confirmed in the record.
When to use this code
Use C54.2 when the provider diagnoses a primary malignant neoplasm of the myometrium. It is appropriate for pathology-confirmed disease, imaging-supported documentation, or operative notes that clearly localize the cancer to the myometrium. If the site is unclear, check documentation.
Do not use for
Do not use this code for benign uterine tumors, endometrial cancer, or malignancy documented only as “uterine cancer” without myometrial involvement. Check documentation if the primary site is uncertain.
Coding tip
Code the most specific uterine site documented; if the note says only “uterus” or “gynecologic malignancy,” query for clarification before assigning C54.2.