ICD-10 Code C50.221 – Malignant neoplasm of upper-inner quadrant of right male breast (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Malignant neoplasm of upper-inner quadrant of right male breast is C50.221.
2026 ICD-10-CM Diagnosis Code C50.221 – Malignant neoplasm of upper-inner quadrant of right male breast

What it is

This code identifies a malignant tumor in the upper-inner quadrant of the right breast in a male patient. Use it when the documentation specifies both the right side and the upper-inner breast location.

Clinical signs

Clinical features may include a palpable breast mass, nipple changes, skin dimpling, or local breast pain. Clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents primary breast cancer in the upper-inner quadrant of the right male breast. It is appropriate for confirmed malignancy, not for suspected disease or a nonspecific breast mass. If the site is described differently, code the documented location.

Do not use for

Do not use it for benign breast lesions, in situ disease, or cancer of an unspecified breast quadrant. Check documentation if the record does not clearly state the right upper-inner quadrant.

Coding tip

Capture laterality and quadrant exactly as documented, because missing site details can lead to a different ICD-10 code.

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