ICD-10 Code B42.81 – Cerebral sporotrichosis (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B42.81 – Cerebral sporotrichosis
What it is
Cerebral sporotrichosis is a fungal infection caused by Sporothrix species that involves the brain or central nervous system. Use this code when documentation specifically identifies cerebral involvement.
Clinical signs
Clinical features vary; refer to documentation. Reported findings may include focal neurologic deficits, seizures, headache, or altered mental status when the infection affects the brain.
When to use this code
Use B42.81 when the provider documents cerebral sporotrichosis, CNS sporotrichosis, or brain involvement due to Sporothrix infection. It may appear in confirmed cases with imaging, pathology, or specialist assessment supporting cerebral disease. If the record only notes sporotrichosis without CNS involvement, check documentation.
Do not use for
Do not use this code for cutaneous, lymphocutaneous, pulmonary, or other non-cerebral sporotrichosis. Avoid it when the chart does not clearly identify brain or central nervous system involvement.
Coding tip
Code only when the provider links sporotrichosis to cerebral involvement; otherwise, query or use the documented site.