ICD-10 Code B39.5 – Histoplasmosis duboisii (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Histoplasmosis duboisii is B39.5.
2026 ICD-10-CM Diagnosis Code B39.5 – Histoplasmosis duboisii

What it is

B39.5 identifies Histoplasma duboisii infection, also called African histoplasmosis. It is a fungal disease that usually affects skin, lymph nodes, and bone rather than the lungs.

Clinical signs

Clinical features vary; refer to documentation. Commonly reported findings include nodules, ulcers, abscesses, enlarged lymph nodes, and bone lesions in patients with compatible fungal infection.

When to use this code

Use B39.5 when the provider documents histoplasmosis duboisii, African histoplasmosis, or infection due to Histoplasma duboisii. The record should support this specific organism or clinical diagnosis. If the note only says histoplasmosis without species, check documentation.

Do not use for

Do not use B39.5 for unspecified histoplasmosis or for pulmonary histoplasmosis without documentation of H. duboisii. If the condition is another fungal infection, choose the code that matches the documented organism.

Coding tip

Code the organism named in the chart, and query when histoplasmosis is documented without species.

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