ICD-10 Code B39.3 – Disseminated histoplasmosis capsulati (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B39.3 – Disseminated histoplasmosis capsulati
What it is
B39.3 identifies disseminated infection caused by Histoplasma capsulatum. Use it when the organism has spread beyond the lungs and documentation supports widespread disease.
Clinical signs
Clinical features vary; refer to documentation. Common findings may include fever, weight loss, fatigue, hepatosplenomegaly, lymphadenopathy, or involvement of multiple organ systems.
When to use this code
Use B39.3 when the record clearly states disseminated histoplasmosis capsulati or disseminated histoplasmosis due to Histoplasma capsulatum. It fits systemic disease, not isolated pulmonary infection. If the note only says histoplasmosis without spread, check documentation before assigning this code.
Do not use for
Do not use this code for localized pulmonary histoplasmosis or other fungal infections. If dissemination is not documented, or the species is different, choose the more specific confirmed diagnosis.
Coding tip
Look for explicit terms such as “disseminated,” “systemic,” or multi-organ involvement before coding B39.3.