ICD-10 Code B39 – Histoplasmosis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Histoplasmosis is B39.
2026 ICD-10-CM Diagnosis Code B39 – Histoplasmosis

What it is

B39 identifies histoplasmosis, a fungal infection caused by Histoplasma species. It most often affects the lungs, but it can also spread beyond the respiratory system.

Clinical signs

Clinical features vary; refer to documentation. Common findings include cough, fever, chest discomfort, fatigue, and evidence of pulmonary or disseminated fungal infection.

When to use this code

Use B39 when the provider documents histoplasmosis without a more specific site or manifestation. It also applies when the record confirms histoplasma infection but does not specify acute, chronic, or disseminated form. Code to the highest documented specificity when available.

Do not use for

Do not use B39 for suspected histoplasmosis without confirmation if the record does not support a diagnosis. Do not substitute it for other fungal infections or for unrelated pulmonary conditions.

Coding tip

Check the note for the exact histoplasmosis type and anatomic site before assigning B39.

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