ICD-10 Code H35.133 – Retinopathy of Prematurity, Stage 2, Bilateral (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Retinopathy of prematurity, stage 2, bilateral is H35.133.
2026 ICD-10-CM Diagnosis Code H35.133 – Retinopathy of prematurity, stage 2, bilateral

What it is

H35.133 identifies retinopathy of prematurity affecting both eyes at stage 2. Use it when documentation shows this specific severity and laterality in a premature infant.

Clinical signs

Stage 2 retinopathy is marked by a distinct ridge at the junction of vascular and avascular retina. Clinical features vary; refer to documentation for eye findings and bilateral involvement.

When to use this code

Use this code when the provider documents bilateral stage 2 retinopathy of prematurity, including during screening follow-up or ophthalmology assessment. It applies only when the diagnosis is confirmed in both eyes. If laterality or stage is unclear, check documentation.

Do not use for

Do not use this code for retinopathy of prematurity in one eye only, or for a different stage. Do not assign it if the record does not specify bilateral stage 2 disease.

Coding tip

Confirm both stage and laterality in the ophthalmology note before assigning H35.133.

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