ICD-10 Code B27.90 – Infectious mononucleosis, unspecified without complication (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Infectious mononucleosis, unspecified without complication is B27.90.
2026 ICD-10-CM Diagnosis Code B27.90 – Infectious mononucleosis, unspecified without complication

What it is

B27.90 identifies infectious mononucleosis when the provider does not specify the causative agent and no complication is documented. Use it for the uncomplicated form of this viral syndrome.

Clinical signs

Typical findings include fever, sore throat, fatigue, and swollen lymph nodes, often with enlarged tonsils or spleen. Clinical features vary; refer to documentation.

When to use this code

Use B27.90 when the record states infectious mononucleosis, mononucleosis, or mono without naming the virus and without documenting complications. It also fits cases described as uncomplicated or not otherwise specified. If the note identifies a specific organism or complication, code that instead.

Do not use for

Do not use this code if the chart documents a specific cause, such as cytomegaloviral mononucleosis, or if complications are present. Check documentation for alternative codes.

Coding tip

Confirm both “unspecified” and “without complication” in the provider note before assigning B27.90.

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