ICD-10 Code B27.9 – Infectious mononucleosis, unspecified (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Infectious mononucleosis, unspecified is B27.9.
2026 ICD-10-CM Diagnosis Code B27.9 – Infectious mononucleosis, unspecified

What it is

B27.9 identifies infectious mononucleosis when the provider documents mono or EBV-related illness without naming a specific subtype. Use it for a nonspecific diagnosis of the condition.

Clinical signs

Typical findings include fever, sore throat, fatigue, and enlarged lymph nodes. Clinical features vary; refer to documentation for splenomegaly, atypical lymphocytosis, or other confirmed findings.

When to use this code

Use this code when the record clearly states infectious mononucleosis but does not specify another ICD-10-CM subtype. It also fits cases documented as unspecified mono after evaluation. If the note names a different organism or a more specific form, code that instead.

Do not use for

Do not use B27.9 when the provider documents a specific infectious mononucleosis type, such as due to another named virus. Check documentation if the chart only mentions “viral illness” or “pharyngitis.”

Coding tip

Code the most specific mononucleosis type documented; if the subtype is not stated, B27.9 is appropriate.

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