ICD-10 Code B25.9 – Cytomegaloviral disease, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B25.9 – Cytomegaloviral disease, unspecified
What it is
B25.9 identifies cytomegaloviral disease when the record confirms CMV infection or illness but does not specify the organ system or complication. Use it for documented CMV disease without a more precise subtype.
Clinical signs
Clinical features vary; refer to documentation. CMV disease may present with systemic illness or organ involvement, but the chart must support the diagnosis rather than simple exposure or past infection.
When to use this code
Use B25.9 when the provider documents cytomegaloviral disease and no site-specific code is available in the note. It also fits cases where CMV is confirmed, but the record does not name retinitis, pneumonitis, hepatitis, or another specific manifestation.
If the documentation only mentions CMV serology, history, or screening without active disease, this code is usually not appropriate. Check documentation for current infection, symptoms, or an explicit diagnosis.
Do not use for
Do not use this code for asymptomatic CMV infection, exposure, or historical CMV without active disease. If a more specific CMV diagnosis is documented, code that condition instead.
Coding tip
Choose B25.9 only when CMV disease is documented but the manifestation is not specified; otherwise, select the more precise CMV code.