ICD-10 Code H21.269 – Iris atrophy (essential) (progressive), unspecified eye (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code H21.269 – Iris atrophy (essential) (progressive), unspecified eye
What it is
This code identifies progressive, essential atrophy of the iris when the affected eye is not specified. It refers to thinning or degeneration of iris tissue, not a separate inflammatory or traumatic eye disorder.
Clinical signs
Clinical features vary; refer to documentation. Findings may include visible iris thinning, transillumination defects, or abnormal pupil shape when recorded by the eye specialist.
When to use this code
Use H21.269 when the provider documents essential or progressive iris atrophy and does not name the laterality. It is appropriate for ophthalmology notes, problem lists, or claims that describe iris degeneration without another primary cause.
If the record identifies a specific eye, code the laterality instead. Check documentation when the chart also mentions trauma, uveitis, or another iris disorder.
Do not use for
Do not use this code for iris changes due to injury, inflammation, or other defined eye diseases. Check documentation if the condition is described as secondary rather than essential.
Coding tip
Always look for laterality and underlying cause before assigning H21.269; unspecified eye should be used only when the record truly leaves the eye undefined.