ICD-10 Code H21.259 – Iridoschisis, unspecified eye (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Iridoschisis, unspecified eye is H21.259.
2026 ICD-10-CM Diagnosis Code H21.259 – Iridoschisis, unspecified eye

What it is

Iridoschisis is a rare condition in which the iris stroma splits into layers, often with a frayed or shredded appearance. This code identifies the disorder when the affected eye is not specified.

Clinical signs

Findings may include iris splitting, loose anterior iris fibers, and a visible disorganized iris surface on eye examination. Clinical features vary; refer to documentation.

When to use this code

Use H21.259 when the provider documents iridoschisis but does not identify the right or left eye. It is appropriate for ophthalmology notes, exam findings, or problem lists that clearly state the diagnosis. If the record later specifies laterality, code that more specific option instead.

Do not use for

Do not use this code for other iris disorders, such as trauma-related iris damage or simple iris atrophy, unless iridoschisis is specifically documented. Check documentation.

Coding tip

Always verify laterality in the chart before assigning the unspecified-eye code.

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