ICD-10 Code H21.23 – Degeneration of iris (pigmentary) (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Degeneration of iris (pigmentary) is H21.23.
2026 ICD-10-CM Diagnosis Code H21.23 – Degeneration of iris (pigmentary)

What it is

This code identifies pigmentary degeneration of the iris, a structural change in the colored part of the eye. Use it when documentation specifically states pigmentary degeneration rather than a broader iris disorder.

Clinical signs

Findings may include visible pigment changes or atrophy of the iris on eye examination. Clinical features vary; refer to documentation for the exact ophthalmic description.

When to use this code

Use H21.23 when the provider documents pigmentary degeneration of the iris as the diagnosis being treated or evaluated. It is appropriate for ophthalmology notes, consults, or problem lists that clearly name this condition. If the record only says “iris abnormality,” check documentation before assigning this code.

Do not use for

Do not use this code for other iris diseases, trauma, or nonspecific pigment dispersion unless the record specifically identifies pigmentary degeneration. Check documentation if the diagnosis is uncertain.

Coding tip

Code only when the provider names pigmentary degeneration of the iris; otherwise, query or code the documented iris condition more precisely.

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