ICD-10 Code B16.0 – Acute hepatitis B with delta-agent with hepatic coma (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B16.0 – Acute hepatitis B with delta-agent with hepatic coma
What it is
This code identifies an acute hepatitis B infection occurring with delta agent, also called hepatitis D, and complicated by hepatic coma. Use it when documentation shows both the acute HBV infection and coma due to liver failure.
Clinical signs
Clinical features may include acute jaundice, malaise, nausea, and evidence of severe liver dysfunction. Hepatic coma indicates altered mental status from liver failure; clinical features vary, so refer to documentation.
When to use this code
Use B16.0 when the provider documents acute hepatitis B with delta agent and explicitly states hepatic coma. The record should support an acute viral hepatitis picture, not chronic infection. If the delta agent or coma is not clearly documented, check documentation before assigning this code.
Do not use for
Do not use this code for acute hepatitis B without delta agent, or for chronic hepatitis B with delta agent. Do not assign it when coma is unrelated to hepatic failure.
Coding tip
Confirm both the acute hepatitis B diagnosis and the hepatic coma linkage in the note before coding.