ICD-10 Code H16.321 – Diffuse interstitial keratitis, right eye (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Diffuse interstitial keratitis, right eye is H16.321.
2026 ICD-10-CM Diagnosis Code H16.321 – Diffuse interstitial keratitis, right eye

What it is

H16.321 identifies diffuse interstitial keratitis affecting the right eye. It refers to inflammation and scarring within the corneal stroma, not the surface epithelium.

Clinical signs

Common findings include corneal haze, stromal inflammation, and reduced visual clarity in the right eye. Clinical features vary; refer to documentation.

When to use this code

Use this code when the provider documents diffuse interstitial keratitis specifically in the right eye. It is appropriate when the record identifies corneal stromal inflammation without a more specific alternative diagnosis. If laterality is not stated, check documentation before coding.

Do not use for

Do not use this code for keratitis limited to the left eye, both eyes, or unspecified laterality. Do not assign it for other corneal disorders unless interstitial keratitis is explicitly documented.

Coding tip

Confirm the eye laterality and the exact term “diffuse interstitial keratitis” before assigning H16.321.

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