ICD-10 Code H16.23 – Neurotrophic keratoconjunctivitis (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Neurotrophic keratoconjunctivitis is H16.23.
2026 ICD-10-CM Diagnosis Code H16.23 – Neurotrophic keratoconjunctivitis

What it is

H16.23 identifies neurotrophic keratoconjunctivitis, a corneal disorder caused by reduced corneal sensation. The cornea and conjunctiva become vulnerable to injury because normal protective reflexes are impaired.

Clinical signs

Clinical features vary; refer to documentation. Typical findings may include decreased corneal sensitivity, persistent epithelial defects, poor healing, and corneal surface breakdown.

When to use this code

Use H16.23 when the provider documents neurotrophic keratoconjunctivitis or neurotrophic keratitis affecting the cornea and conjunctiva. Code it when the record links the condition to impaired corneal innervation and related surface disease. Check documentation if the note only describes nonspecific keratitis.

Do not use for

Do not use this code for routine conjunctivitis, dry eye alone, or corneal injury without documented neurotrophic involvement. If the diagnosis is uncertain, check documentation rather than assuming H16.23.

Coding tip

Confirm the provider’s wording includes neurotrophic keratoconjunctivitis, not just corneal ulcer or keratitis, before assigning H16.23.

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