ICD-10 Code H16.22 – Keratoconjunctivitis sicca, not specified as Sjögren’s (2026): Diagnosis, Symptoms & Billing Guide

The ICD-10 code for Keratoconjunctivitis sicca, not specified as Sjögren’s is H16.22.
2026 ICD-10-CM Diagnosis Code H16.22 – Keratoconjunctivitis sicca, not specified as Sjögren’s

What it is

This code identifies dry eye disease with corneal and conjunctival involvement when Sjögren’s syndrome is not specified. It indicates keratoconjunctivitis sicca as the documented diagnosis.

Clinical signs

Typical findings include ocular dryness, burning, irritation, foreign-body sensation, and redness. Clinical features vary; refer to documentation.

When to use this code

Use H16.22 when the provider documents keratoconjunctivitis sicca and does not attribute it to Sjögren’s syndrome. It also fits charted dry eye with corneal and conjunctival involvement when the record supports this diagnosis. Check documentation if the cause is unclear.

Do not use for

Do not use this code when the record specifies Sjögren’s-related dry eye or another underlying disorder. Do not assign it for nonspecific eye irritation without a documented diagnosis.

Coding tip

Confirm that the note states keratoconjunctivitis sicca and that Sjögren’s is not documented before assigning H16.22.

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