ICD-10 Code B08.011 – Vaccinia not from vaccine (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code B08.011 – Vaccinia not from vaccine
What it is
Vaccinia not from vaccine is an infection caused by vaccinia virus that is not linked to vaccination. Use this code when documentation identifies a natural or accidental vaccinia infection rather than a vaccine-related reaction.
Clinical signs
Clinical features can include localized skin lesions, pustules, or ulcerative lesions, sometimes with regional lymph node swelling. Clinical features vary; refer to documentation.
When to use this code
Use B08.011 when the provider documents vaccinia infection and clearly states it is not from vaccine exposure. It is appropriate for confirmed or suspected non-vaccine vaccinia cases when the record supports the diagnosis. Check documentation if the source of infection is unclear.
Do not use for
Do not use this code for routine smallpox vaccination reactions or other post-vaccination adverse effects. If the condition is described only as a vaccine complication, choose the more specific documented code.
Coding tip
Confirm whether the note says “not from vaccine” before assigning B08.011.