ICD-10 Code G61.1 – Serum neuropathy (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code G61.1 – Serum neuropathy
What it is
G61.1 identifies serum neuropathy, a peripheral nerve disorder that occurs after exposure to foreign serum or similar immune triggers. It reflects an immune-mediated neuropathic reaction rather than a primary nerve disease.
Clinical signs
Clinical features vary; refer to documentation. Typical findings may include new neuropathic symptoms after serum exposure, such as sensory changes, weakness, or reduced reflexes, with timing that supports an immune reaction.
When to use this code
Use this code when the provider documents serum neuropathy or a neuropathy attributed to serum exposure. It may also fit cases described as a post-serum immune neuropathic reaction when the record clearly links the condition to that exposure.
Do not assume this diagnosis from nonspecific neuropathy alone. You should verify the causal relationship and the documented clinical assessment before assigning G61.1.
Do not use for
Do not use G61.1 for unrelated peripheral neuropathies, toxic neuropathy, or neuropathy with no documented serum exposure. Check documentation if the cause is unclear.
Coding tip
Code G61.1 only when the record explicitly ties the neuropathy to serum exposure or serum-induced reaction.