ICD-10 Code G31.80 – Leukodystrophy, unspecified (2026): Diagnosis, Symptoms & Billing Guide
2026 ICD-10-CM Diagnosis Code G31.80 – Leukodystrophy, unspecified
What it is
Leukodystrophy, unspecified refers to a disorder affecting the brain’s white matter, but the exact type has not been identified in the record. Use this code when documentation confirms leukodystrophy without naming a specific subtype.
Clinical signs
Clinical features vary; refer to documentation. Commonly reported findings include progressive neurologic decline, motor impairment, developmental delay, or gait and coordination problems.
When to use this code
Use G31.80 when the provider documents leukodystrophy and does not specify the inherited or acquired form. It may also fit when records mention white matter disease consistent with leukodystrophy, but the diagnosis remains unclassified. Check documentation if the note names a more specific disorder.
Do not use for
Do not use this code if the chart identifies a specific leukodystrophy subtype or another defined neurologic disorder. Avoid it when the documentation only describes nonspecific white matter changes without a diagnosis of leukodystrophy.
Coding tip
Code the most specific leukodystrophy documented; if the subtype is missing, G31.80 is the default.